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Original Research |

Unilateral Hyperlucent Lung: A Physiologic Syndrome

Ann Intern Med. 1965;62(4):675-684. doi:10.7326/0003-4819-62-4-675
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A unilateral hyperlucent lung in association with agenesis of a pulmonary artery was first described by Madoff, Gaensler, and Strieder (1) in 1952. In 1953 Swyer and James (2) reported the first case of a unilateral hyperlucent lung with a small pulmonary artery and poor bronchographic filling of the peripheral bronchi. MacLeod (3) then reported nine other patients with a hypoplastic artery, three of whom had localized distal bronchiectasis. Further descriptions of this syndrome have been variable, and it has previously been considered to be uncommon (1-22).

The recognition of five new cases of unilateral hyperlucent lung syndrome in a


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