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Treatment of Acute and Chronic Respiratory Acidosis with a Volume-cycled Respirator.

Stephen N. Ayres, M.D. (Associate); Stanley Giannelli Jr., M.D.; Antoinette Criscitiello, R.N., M.S.; and Ruth G. Armstrong, R.N., B.S.
Ann Intern Med. 1965;62(5):1096. doi:10.7326/0003-4819-62-5-1096_1
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Respiratory acidosis can be treated best by a mechanical ventilator that both increases alveolar ventilation and decreases respiratory work and carbon dioxide production. The low flow oxygen method is ineffective and dangerous; recent studies suggest that pressure-cycled intermittent positive pressure breathing devices may be ineffective in ventilating patients with markedly abnormal lung or chest wall compliances, since the required pressures may be impossible to attain in such patients. Analysis of blood gas and expired air in 13 patients with acute or chronic respiratory acidosis demonstrate the advantages of a volume-cycled piston respirator (Morch) over a pressure-cycled respirator. Most striking is


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