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Esophageal Motility in Neuromuscular Disorders

ROBERT A. FISCHER, M.D.; GEORGE W. ELLISON, M.D.; WALTER R. THAYER, M.D.; HOWARD M. SPIRO, M.D., F.A.C.P.; and GILBERT H. GLASER, M.D.
Ann Intern Med. 1965;63(2):229-248. doi:10.7326/0003-4819-63-2-229
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This excerpt has been provided in the absence of an abstract.

One of the frequent problems in patients with neuromuscular disorders is swallowing dysfunction, often leading to a severe nutritional disturbance. Swallowing is a complex phenomenon comprised of the transfer of food from the mouth into the oropharynx, its transport through the esophagus, and its entrance into the stomach. Swallowing is usually an act involving voluntary initiation at a cerebral level with transmission along corticobulbar pathways to the medulla. Transfer combines this volitional act with reflex activity mediated via the glossopharyngeal and vagus nerves in such a way that once the swallow begins it continues through the oropharynx and pharyngeal-esophageal sphincter

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