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Hemolytic Anemia Due to a Defective Teflon Aortic Valve Prosthesis

Ann Intern Med. 1965;63(2):295-301. doi:10.7326/0003-4819-63-2-295
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As the techniques of cardiac surgery have been refined, with the use of various new heart-lung machines and intracardiac prostheses and with the ultimate possibility of a successful artificial heart, increasing attention has been focused on the effect of these devices on the circulating erythrocytes. Transient anemia, one of the manifestations of the "postperfusion" syndrome described by Kreel and associates (1) and Wheeler, Turner, and Scannell (2), is now frequently recognized. After several months, these patients have no evidence of a residual hemolytic process.

In sharp contrast are seven reported cases of severe, prolonged intravascular hemolysis after the repair with


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