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Abstracts |

Psychiatric Disturbances in Wilson's Disease.

I. Herbert Scheinberg, M.D.
Ann Intern Med. 1965;63(5):916. doi:10.7326/0003-4819-63-5-916_2
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Wilson's disease, or chronic copper toxicity, occurs in individuals with an inherited metabolic defect that causes an abnormally high retention of dietary copper. In roughly one third of the patients, the first clinical manifestation of the illness is psychiatric as exemplified by the following three patients: one man, in whom paranoid delusions were later revealed, murderously assaulted a fellow worker; a young adult was arrested for Peeping Tom activities; an adolescent girl was taken to a psychoanalyst for pronounced emotional disturbance. Some patients have been found as undiagnosed inmates of mental hospitals. In perhaps half of the patients in whom


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