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Abstracts |

Chronic Pyelonephritis—Essential or Primary Versus Secondary.

Harry Seneca, M.D., F.A.C.P.
Ann Intern Med. 1965;63(5):920. doi:10.7326/0003-4819-63-5-920_2
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Bacteriological, immunological, and clinical survey of 30 cases of essential or primary and 84 cases of secondary (calculus or obstructive) pyelonephritis reveal that: (1) Essential pyelonephritis is a very serious disease having a higher mortality rate than secondary pyelonephritis; (2) in secondary pyelonephritis, after the surgical management of the urological pathology, chemotherapy controls or cures the infection. In essential pyelonephritis, chemotherapy fails to control the infection. Prolonged suppressive therapy helps; (3) in essential pyelonephritis, the mechanism of antibody production or immunity is inadequate. In 30 cases of essential pyelonephritis, 57 pathogens were cultured from the urine, and the blood sera


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