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A Syndrome Resembling Infectious Mononucleosis After Splenectomy for Idiopathic Thrombocytopenic Purpura

Ann Intern Med. 1965;63(6):965-971. doi:10.7326/0003-4819-63-6-965
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Thirty-four splenectomies for idiopathic thrombocytopenic purpura were performed at the Henry Ford Hospital from January, 1955, to February, 1965. Twenty-one of these patients had chronic idiopathic thrombocytopenic purpura, and 13 had acute cases. Of these, the authors recognized three instances of apparent infectious mononucleosis that occurred during surgical convalescence and that had its onset 3 to 5 weeks after splenectomy. The cases occurred sporadically, one each in 1957, 1960, and 1965. Two of these occurred in patients with chronic idiopathic thrombocytopenic purpura and one in a patient with an acute case. Thus, the incidence of this course of events was


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