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The Cortisone-Glucose Tolerance Test: The Influence of Age on Performance

THOMAS POZEFSKY, M.D.; JOEL L. COLKER, M.D.; HAROLD M. LANGS, M.D.; and REUBIN ANDRES, M.D.
Ann Intern Med. 1965;63(6):988-1000. doi:10.7326/0003-4819-63-6-988
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At any given time there exists a group of individuals who, although reacting normally to standard tests of glucose tolerance, are destined to become overt diabetics in the future. The development of abnormal glucose tolerance in a sense represents a late stage in the natural history of diabetes. The ability to detect the diabetic diathesis at a stage of the disease before the development of grossly abnormal glucose tolerance would be of great theoretical interest and potentially of practical importance as well. The introduction of the cortisone-glucose tolerance test by Fajans and Conn (1) 11 years ago for the purpose

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glucose ; cortisone

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