0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Editorials |

Sodium Fluoride in the Treatment of Osteoporosis and Other Bone Diseases

PETER H. ADAMS, M.B.; and JENIFER JOWSEY, D.PHIL.
[+] Article and Author Information

Section of Surgical Research
Mayo Clinic and Mayo Foundation
Rochester, Minn.


Ann Intern Med. 1965;63(6):1151-1155. doi:10.7326/0003-4819-63-6-1151
Text Size: A A A
This excerpt has been provided in the absence of an abstract.

In a study of workers exposed to cryolite (sodium aluminum fluoride) dust for many years, Roholm (1) found that some had severe chronic skeletal fluorosis but that in a greater number there was radiologic evidence of osteosclerosis which was not associated with symptoms. This observation led Rich and Ensinck (2) to administer sodium fluoride to patients with rarefying disorders of the skeleton in the belief that the production of a mild degree of asymptomatic osteosclerosis would strengthen the bone. Since then, several investigators have reported their experiences with sodium fluoride therapy in patients with osteoporosis (3-5), osteitis deformans (3, 6,

...

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Related Point of Care
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)