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The Association of Cancer and the Nephrotic Syndrome

Ann Intern Med. 1966;64(1):41-51. doi:10.7326/0003-4819-64-1-41
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Within recent years there has been increasing interest in malignant tumors with systemic manifestations resembling several of the auto-immune diseases. In a recent review, Greenberg, Divertie, and Woolner (1) have summarized many of these manifestations and have stressed the possibility that the recognition of these syndromes may be an early clue to the diagnosis of cancer. The mechanism of this relationship is not understood in many instances.

An immune response of the host to components of his tumor or catabolic products therefrom has occasionally been suspected of playing an etiologic role in producing manifestations resembling dermatomyositis (2-5), chronic lymphocytic thyroiditis


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