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Liver Transplantation

THOMAS E. STARZL, M.D., PH.D.; THOMAS L. MARCHIORO, M.D.; and TANOUS D. FARIS, M.D.
Ann Intern Med. 1966;64(2):473-477. doi:10.7326/0003-4819-64-2-473
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During the last few years there has been mounting interest in the possibility that homotransplantation may be an effective technique for the treatment of various diseases that affect primarily a single organ system. There are sound reasons for this enthusiasm. Many patients have had considerable prolongation of life by virtue of chronically functioning renal homografts; in our experience more than 50% of the patients treated from 1½ to 3 years ago are still alive, having had continuous urine excretion by their new kidneys during these intervals.

In view of these encouraging results and those from several other centers (1), it

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