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Abstracts |

Successful Therapy of Previously Intractable Gout.

Elmer C. Bartels, M.D., F.A.C.P.
Ann Intern Med. 1966;64(5):1173. doi:10.7326/0003-4819-64-5-1173_2
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Three phases of gout management have now been well delineated—the preuricosuric, the uricosuric, and the anti-uric acid. During the first phase satisfactory control was not possible so therapy was chiefly symptomatic. With the advent of the uricosuric drugs, control of gout in almost all patients was feasible; reversible changes (decrease in size of tophi and bone recalcification) were observed in those with advanced tophaceous gout. In patients with associated gouty nephritis or complicating renal disease (nephrosclerosis, glomerulonephritis, pyelonephritis) gout commonly remained uncontrolled since usually a satisfactory uricosuric response could not be accomplished. There were some patients who could not tolerate

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