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Isolated Lactase Deficiency Producing Postgastrectomy Milk Intolerance

Ann Intern Med. 1966;64(6):1252-1258. doi:10.7326/0003-4819-64-6-1252
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The ingestion of milk and milk products may precipitate postprandial symptoms in some patients after gastric surgery for peptic ulcer disease (1). Milk allergy (2), location of the gastrojejunal anastomosis (3), and intestinal lactase deficiency (4) have been suggested as possible causes. Two patients whose postgastrectomy symptoms were associated with an isolated lactase deficiency were subjects of an earlier report (5). The present investigation expands these observations and evaluates lactose tolerance tests and the intestinal disaccharidase activity in a group of 24 patients who underwent gastric surgery.

MATERIAL AND METHODS: PATIENTSOut of all the subjects, 19 males and 5


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