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The Nonefficacy of Short-term Anabolic Steroid Therapy in Alcoholic Liver Disease

L. FREDERICK FENSTER, M.D.
Ann Intern Med. 1966;65(4):738-744. doi:10.7326/0003-4819-65-4-738
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Anabolic steroids have been advocated as useful therapeutic agents in the management of patients with active cirrhosis. However, despite several glowing reports of a beneficial effect (1-3), controls generally have been lacking. An exception is the experience reported by Wells (4) in which patients with cirrhosis given testosterone propionate parenterally for 14 to 86 weeks were thought to fare better than a placebo-treated group and as well as a prednisolone-treated group. However, the study group consisted of patients with several types of cirrhosis, the duration of therapy varied from patient to patient, and only selected data were presented. More recently,

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