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Abstracts |

Is Injection Therapy in Pollinosis of Value?

Francis C. Lowell, M.D., F.A.C.P.
Ann Intern Med. 1967;66(5):1026. doi:10.7326/0003-4819-66-5-1026_3
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Many view prophylactic injection therapy for pollinosis with skepticism. Indeed, after 50 years of experience one could point to little in its support beyond faith in its value among many physicians and patients. In recent years, however, clinical trials, giving increasing attention to experimental design, have tended to justify this faith, although lingering doubts remain. In the course of these efforts it has become clear that such trials present a particularly difficult challenge.

The manner in which one can overcome the difficulties inherent in these clinical trials is described. The results of studies are presented, lending strong support for the


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