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Abstracts |

Acute Renal Failure Associated with Heat Stress and Physical Exertion.

Robert W. Schrier; Haller S. Henderson; C. Craig Tisher; and Richard L. Tannen
Ann Intern Med. 1967;66(5):1053. doi:10.7326/0003-4819-66-5-1053_1
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Eight cases of acute renal failure associated with heat stress and physical exercise were treated at the Walter Reed General Hospital between 1960 and 1966. All of the cases occurred during the summer in recruits participating in their initial 2 months of basic training.

Several unique characteristics of the clinical course were marked hypercatabolism, muscle damage, and prolonged periods of anuria. Hypercatabolism was evidenced by rapidly rising blood urea nitrogen and serum potassium levels. In some cases frequent peritoneal dialysis did not prevent a gradual increase in azotemia. Diffuse muscle involvement was found histologically in three fatal cases, including vacuolization,


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