The full content of Annals is available to subscribers

Subscribe/Learn More  >
Articles |

Hereditary Pancreatitis: A Kindred Without Gross Aminoaciduria

Ann Intern Med. 1968;68(1):88-96. doi:10.7326/0003-4819-68-1-88
Text Size: A A A

A seventh kindred with hereditary pancreatitis is reported. Of the 71 members data were obtained on 55, and 18 of the 55 were examined by the authors. Six members had definite pancreatitis, and 5 had suspected pancreatitis. The mode of genetic transmission is non-sex-linked and appears to be autosomal dominant. The disease is characterized by onset in childhood of recurrent episodes of abdominal pain and is frequently accompanied by pancreatic calcifications, diabetes mellitus, and steatorrhea.

Comparison of this kindred with the six kindreds reported previously reveals many similarities. The present kindred and the five kindreds reported from the Mayo Clinic differ from the kindred reported from France in the clinical course, the pathologic state of the pancreas, and the results of surgery. The present kindred differs from those reported from the Mayo Clinic in that measurements of the alpha-amino nitrogen in the urine indicate that hereditary pancreatitis can exist in the absence of gross aminoaciduria. Aminoaciduria, measured by paper chromatography, was also absent in the kindred in France. While the findings may be similar in the various members of a kindred with hereditary pancreatitis, there may be differences among the kindreds.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
Hereditary pancreatitis--a case report. Z Gastroenterol 1994;32(11):645-6.
Hereditary pancreatitis. Gastroenterol Clin North Am 1994;23(4):743-52.
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.