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Abstracts |

The William C. Menninger Memorial Lecture: Some Psychobiological Determinants of Somatic Disease.

George L. Engel, M.D.
Ann Intern Med. 1968;68(5):1140. doi:10.7326/0003-4819-68-5-1140_3
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One of the most firmly held folk notions has been that despair, gloom, grief, loneliness, misfortune, and the like predispose to disease, while faith, confidence, tranquility, and peace of mind aid recovery and insure health. One discovers such themes repeatedly in the myths, legends, folklore, and literature of all peoples. Physicians, too, have held such beliefs, particularly in the romantic era of the nineteenth century, just before the flowering of modern scientific medicine. Even in modern times physicians grudgingly acknowledge from time to time that they have encountered instances in which such influences seem to have been prepotent. Yet among


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