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Abstracts |

Clinical Experience with Lipid Dialysate.

Billy J. Matter, M.D. (Associate); M. Earl Ginn, M.D.; James H. Shinaberger, M.D.; and Joel B. Mann, M.D.
Ann Intern Med. 1968;68(5):1143. doi:10.7326/0003-4819-68-5-1143_1
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Dialysis utilizing aqueous solutions is an established procedure in the treatment of poisoning due to water-soluble intoxicants. However, many frequently prescribed drugs with high lipid to water partition coefficients are not effectively removed by aqueous dialysate. To augment transfer of these compounds we developed a lipid dialysate system. Soybean oil was found to be effective and nontoxic. It is inexpensive and readily available. Due to the high solubility of these compounds in oil, only 1 to 5 gal need be used. Kiil, Klung, and twin-coil dialyzers have been successfully utilized. This technique has been effectively used in the clinical treatment


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