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Abstracts |

Thyroid Function in Patients with Serum Long-Acting Thyroid Stimulator.

T. D. R. Hockaday, M.R.C.P.; and D. el Kabir, D.Phil.
Ann Intern Med. 1968;68(5):1144. doi:10.7326/0003-4819-68-5-1144_1
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Blood was taken from all the 365 patients on whom diagnostic radioactive iodine studies were performed in Oxford during 1966 and the unextracted serum assayed for long-acting thyroid stimulator (LATS) by a modification of the McKenzie bioassay.

LATS was detected in 20 patients, while 80 of the 365 had thyroid overactivity by both the radioactive iodine study and clinical examination combined with other thyroid function tests. Seventy of the nontoxic patients had clinical evidence of nodular goiters. On comparison of the 3 groups of patients, those with detectable LATS, those with thyrotoxicity and no LATS detected, and those with nontoxic


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