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Abstracts |

Course of Muscular Subaortic Stenosis.

Brent M. Parker, M.D.
Ann Intern Med. 1968;68(5):1160. doi:10.7326/0003-4819-68-5-1160_1
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Although much has been written about the surgical treatment of hypertrophic muscular subaortic stenosis, little attention has been given to the natural history of patients with this disease followed without surgery. The course of 14 patients followed medically will be compared with published surgical results. Diagnosis of muscular subaortic stenosis was established in all 14 patients by left heart catheterization. Age ranged from 16 to 48. Symptoms included dyspnea (nine), chest pain (five), fatigue (four), and syncope (two). Four patients were asymptomatic. Electrocardiograms showed left ventricular hypertrophy in 12 and patterns resembling anterolateral myocardial infarction in 2. Pressure gradients between


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