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Myeloid Metaplasia: A Study of 98 Cases.

David S. Rosenthal, M.D.; and William C. Moloney, M.D., F.A.C.P.
Ann Intern Med. 1968;68(5):1171-1172. doi:10.7326/0003-4819-68-5-1171_4
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Studies have been carried out over the past 14 years at the Boston City Hospital on 98 cases of myeloid metaplasia (MM). Of these patients, 41 are dead, 30 are alive, and 27 have been lost to follow-up. In addition to the usual clinical and laboratory data, investigations included leukocyte alkaline phosphatase, red cell enzymes, serum B12 and folate levels, marrow biopsy, and cytogenic studies. These findings were compared with studies on 93 cases of chronic granulocytic leukemia (CGL). The difficulties of differentiating MM from CGL are well-known, and 7 cases initially classified as MM were found to be CGL


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