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Cardiac Output in Polycythemia Vera.

P. M. Weber, M.D., F.A.C.P.; M. Pollycove, M.D.; M. Bacaner, M.D.; and J. H. Lawrence, M.D., F.A.C.P.
Ann Intern Med. 1968;68(5):1173. doi:10.7326/0003-4819-68-5-1173_1
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While the influence of acute changes in blood volume and hematocrit (hct) upon cardiac output have been well-documented, the cardiac output in polycythemia vera has been reported variously as increased, unchanged, and decreased. In this study an effort was made to clarify the effects of chronic change in blood volume and hct on cardiac output by studying 32 subjects, 25 with polycythemia vera and 7 who were normal. Some of the patients with polycythemia vera had been treated so that their blood volumes, though not necessarily their hcts, were normal. Therefore, 3 groups were compared; normal subjects (7), polycythemia vera


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