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Abstracts |

Pulmonary Cryptococcosis.

Bayard Tynes, M.D., F.A.C.P.; Kathleen N. Mason, M.S.; and John E. Bennett, M.D. (Associate)
Ann Intern Med. 1968;68(5):1177. doi:10.7326/0003-4819-68-5-1177_2
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Cryptococcus neoformans was isolated from sputum or lung tissue of 26 patients, none of whom had cryptococcal meningitis. Three additional patients with bronchitis had nonpathogenic crytococcal species in their sputum. Twenty-one of 26 were white males. Their occupational history seemed noncontributory, and only 2 had diabetes mellitus. Opportunistic invasion occurred in 6 with malignancy. Pulmonary parenchymal invasion was proved in 4 patients; 3 had thoracotomy for "characteristic infiltrative lesions"; and 1 with Cushing's syndrome, calcified adrenal glands, and a pulmonary infiltrate responded gradually to bilateral adrenalectomy. Tissue invasion was suspected in a young negro male with bilateral hilar adenopathy. Although


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