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The Influence of Original Renal Disease on the Fate of Renal Allografts.

Earl Smith, M.D.; Ray W. Gifford Jr., M.D., F.A.C.P.; Satoru Nakamoto, M.D.; Ralph A. Straffon, M.D.; Kenneth Tung, M.D.; David C. Humphrey, M.D., F.A.C.P.; and Donald G. Vidt, M.D.
Ann Intern Med. 1968;68(5):1183. doi:10.7326/0003-4819-68-5-1183_3
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The results of 132 renal allotransplantations performed in 109 patients at the Cleveland Clinic between January 1963 and October 1966 were reviewed to test the hypothesis that patients with chronic glomerulonephritis, an immunologic disease, should reject transplanted kidneys more readily than patients with other types of renal disease. The 1- and 2-year survival rates for renal allografts obtained from living donors was 78% (18 or 23) and 56% (9 of 16), respectively, for patients with chronic glomerulonephritis compared with 25% at both 1 (2 of 8) and 2 (1 of 4) years for patients with chronic pyelonephritis. The 1-and 2-year


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