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Calcium Absorption and Bone Disease in Obstructive Jaundice.

C. D. Holdsworth, M.R.C.P.; K. A. Kehayoglou, M.D.; and Sheila Sherlock, F.R.C.P.
Ann Intern Med. 1968;68(5):1188. doi:10.7326/0003-4819-68-5-1188_1
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Calcium absorption and bone disease were studied in 12 patients with primary biliary cirrhosis before and after treatment with intramuscular vitamin D. Calcium absorption was assessed by plasma levels of 47Ca and whole-body retention of 47Ca after an oral dose of 47CaCl2 dissolved in water. Before treatment calcium absorption was subnormal in 4 patients. Impairment of calcium absorption correlated well with the depth of jaundice but was unrelated to duration of jaundice. After vitamin D, absorption of 47CaCl2 was significantly improved and became normal in all patients.

Retention in the body of an intravenous infusion of calcium was greater than


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