The patterns of the multisystem disorder, sarcoidosis, in 537 patients in London have been compared with 311 in New York. The clinical diagnosis was always confirmed histologically; in four fifths of each series, sarcoid tissue was obtained by biopsy of lymph node, skin, or liver, which, together with the Kveim test, proved the most fruitful techniques.
The comparison includes clinical, radiological, and biochemical manifestations, modes of presentation, epidemiology, the immunological deficit, and treatment. Despite racial, cultural, and geographical differences, the pattern of disease was similar in both countries.
This scheme will provide a basis for computer analysis on a universal