The full content of Annals is available to subscribers

Subscribe/Learn More  >
Original Research |

Tobacco: A Precipitating Factor in Angina Pectoris

Ann Intern Med. 1968;69(3):529-536. doi:10.7326/0003-4819-69-3-529
Text Size: A A A

Ten patients with classical angina pectoris due to coronary artery disease were exercised in an upright position with a fixed exercise load on a bicycle ergometer until they developed the first manifestation of angina pectoris. They each performed this exercise four times in a nonsmoking state and four times after smoking a cigarette of high nicotine content for 5 min. All subjects developed angina sooner if they smoked before exercising. The average percent of shortening of the exercise period before angina developed in the smoking state as compared with the nonsmoking state was 24. All patients developed an increase in the modified tension-time index after smoking. This increase represents an increase in myocardial oxygen consumption. After exercise, patients with diseased coronary arteries who smoke may not meet the increased demand for myocardial oxygen and, therefore, may develop angina sooner.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Related Point of Care
Topic Collections
PubMed Articles
Tobacco: a precipitating factor in angina pectoris. Ann Intern Med 1968;69(3):529-36.
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.