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Cholera Vaccine: Recommendation on Immunization Practices

Ann Intern Med. 1968;69(4):783-784. doi:10.7326/0003-4819-69-4-783
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Issued by the Advisory Committee on Immunization Practices, U. S. Public Health Service, meeting on February 15, 1968: Cholera generally occurs in endemic and epidemic form only in South and Southeast Asia. In recent years, however, it has also been epidemic in certain areas of the Middle East.Infection is acquired from contaminated water or food. It is believed to result from personal contact only in rare instances.

VACCINE: Various cholera vaccines have been widely used, but until recently their efficacy was unproved. Carefully controlled field studies have now clearly demonstrated the effectiveness of current vaccines against both the classical


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