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Isolated Adrenocorticotrophic Hormone Deficiency in Acute Intermittent Porphyria

ALAN D. WAXMAN, M.D.; PAUL D. BERK, M.D.; DON SCHALCH, M.D.; and DONALD P. TSCHUDY, M.D.
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Bethesda, Maryland; and Rochester, New York


Ann Intern Med. 1969;70(2):317-323. doi:10.7326/0003-4819-70-2-317
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SUMMARY:

A 38-year-old white man with acute intermittent porphyria is presented. This is thought to be the first demonstrated instance of defective adrenocorticotrophic hormone (ACTH) secretion resulting from acute intermittent porphyria. He is one of three patients who have had relief of the pain associated with an attack of acute intermittent porphyria by therapy with insulin and a high carbohydrate intake.

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