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Toxoplasmosis, Lymphoma, or Both?

FLORA M. BARLOTTA, M.D.; MANUEL OCHOA JR., M.D., F.A.C.P.; HAROLD C. NEU, M.D., F.A.C.P.; and JOHN E. ULTMANN, M.D., F.A.C.P.
Ann Intern Med. 1969;70(3):517-528. doi:10.7326/0003-4819-70-3-517
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SUMMARY:

Five patients with toxoplasmosis,three with Hodgkin's disease and toxoplasmosis, and two with other lymphomatous disorders and positive toxoplasma titers were studied. Both toxoplasmosis and lymphoma may be characterized by fever, weight loss, lymphadenopathy, hepatosplenomegaly, rash, neurologic abnormalities, anemia, and increased concentration of the serum gamma globulins. Further, the cellular pleomorphism of the lymph node infected with Toxoplasma gondii may make it difficult to distinguish between lymphoma and toxoplasmosis. Since the treatment for these two disorders is different, it is essential to recognize that they can mimic each other.

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