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Original Research |

Adverse Reactions Associated with Cannabis Products in India

Ann Intern Med. 1969;70(3):529-533. doi:10.7326/0003-4819-70-3-529
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Six patients with emotional disorders associated with the use of ganja, bhang, and hashish, products prepared from Cannabis sativa var. indica, by Westerners in India are reported. The major psychiatric problems seen included anxiety reactions of moderate to severe intensity and psychotic reactions of schizophrenic and schizoaffective types. Our experience is compared with that recently reported by others and is found to be similar. The possibility that observed frequencies of serious adverse reactions to cannabis products in different areas may represent different segments of a dose-response curve to active isomers of tetrahydrocannabinol is discussed.

Although current evidence by no means constitutes proof of a causal role for cannabis in emotional disturbance, it is suggested that, until there is further and definitive information as to the effects of cannabis products on the mental health of those who use them, a cautious attitude towards their widespread and unsupervised use is justified.







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