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A Turner's Syndrome Variant with Polycystic Ovaries and Idiopathic Myocardial Hypertrophy

GORDON H. WILLIAMS, M.D.; LESLIE I. ROSE, M.D.; PAUL I. JAGGER, M.D.; and DAVID P. LAULER, M.D.
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Boston, Massachusetts


Ann Intern Med. 1969;70(3):571-576. doi:10.7326/0003-4819-70-3-571
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SUMMARY:

A patient presented with short stature, pterygium colli, cubitus valgus, multiple pigmented nevi, low-set hairline, and hypoplastic nails—all features characteristic of Turner's syndrome. She had oligomenorrhea but normal secondary sexual characteristics, and her chief complaint was chest pain and progressive hirsutism. The buccal smear was positive for Barr bodies, and she had a normal female karyotype. Cardiac catheterization showed idiopathic myocardial hypertrophy, and exploratory laparotomy disclosed polycystic ovaries. The occurrence of Turner's somatotype, polycystic ovaries, and idiopathic myocardial hypertrophy in the same individual has not previously been reported.

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