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Abstracts |

Primary Hyperparathyroidism and Associated Thyroid Disease.

V. O. Laing, M.D.; Boy Frame, M.D., F.A.C.P.; and M. A. Block, M.D.
Ann Intern Med. 1969;70(5):1063. doi:10.7326/0003-4819-70-5-1063_1
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Among 72 (53 female and 19 male) patients with primary hyperparathyroidism 29 (40%) were found to have concomitant pathologic changes in the thyroid. The prevalence of thyroid carcinoma was 5.5%; toxic multinodular goiter, 1.4%; thyroiditis, 4.2%; and gross thyroid nodules, 29.3%. The above figures were compared with the prevalence of thyroid disease found in a random survey of 100 consecutive autopsies (60 females and 40 males) at this hospital, which showed the following: thyroid carcinoma (1%), thyroiditis (1%), and gross thyroid nodules (14%). Possible mechanisms that could help explain the occurrence of combined thyroid-parathyroid disease are discussed. It is felt


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