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Chronic Ulcerative Colitis Beginning in Children and Teenagers.

Marcel Patterson, M.D., F.A.C.P.; Leo Castiglioni, M.D.; and Lloyd Sampson, M.D.
Ann Intern Med. 1969;70(5):1070. doi:10.7326/0003-4819-70-5-1070_2
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This report describes our experience with 43 patients who developed symptoms of chronic ulcerative colitis during childhood or teenage years (1953 to 1966). The clinical picture is similar to that observed in adults except that these patients appear more ill and disabled by their disease. Seventy-one percent of the patients had total colon involvement, and 65% had complications of the disease when first seen. All patients but one have been followed to the present. Six patients (11%) have died: 2 from cancer, 2 from liver failure, and 2 from septicemia. All deaths occurred before age 30. Two patients with disease


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