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The Importance of Methicillin-Resistant Staphylococcus aureus.

E. Jack Benner, M.D., F.A.C.P.; and F. H. Kayser, M.D.
Ann Intern Med. 1969;70(5):1089. doi:10.7326/0003-4819-70-5-1089_1
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Sizable outbreaks of infections caused by methicillin-resistant Staphylococcus aureus have occurred in Europe, England, and now the United States. The clinical significance, epidemiological factors, and antimicrobic susceptibility of these unusual staphylococci have been defined by analysis of 139 isolates containing these organisms. The kinds of infections occurring were those to be expected in nosocomial problems. Patients afflicted with chronic debilitating diseases were the usual victims. At least 50% of the infections were not acquired until at least 21 days of hospitalization, and all were contracted in a hosiptal setting. Infections were a common cause of death; 18 of 29 patients


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