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Glucose Metabolism in Human Adipose Tissue In Vitro.

A. M. Mellati, M.D.; D. Rubenstein, M.D.; and J. C. Beck, M.D.
Ann Intern Med. 1969;70(5):1102. doi:10.7326/0003-4819-70-5-1102_2
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Incorporation of glucose into carbon dioxide fatty acids, and glyceride-glycerol in human adipose tissue in vitro have been studied. Eighty specimens from 59 subjects were all responsive to insulin when added to the incubation medium. Subcutaneous adipose tissue from normal subjects excised an hour after a mixed meal showed an increase in lipogenesis when compared with adipose tissue from the fasting state of the same individuals. Addition of insulin in vitro increased the lipogenesis of Ac and Pc tissue to the same level, indicating that the capacity for lipogenesis remains unaltered after a fast of short duration. In comparing various


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