The full content of Annals is available to subscribers

Subscribe/Learn More  >
Articles |

Left Ventricular Hypertrophy by Electrocardiogram: Prevalence, Incidence, and Mortality in the Framingham Study

Ann Intern Med. 1969;71(1):89-105. doi:10.7326/0003-4819-71-1-89
Text Size: A A A

In a general population sample of 5,209 in Framingham, Mass., the prevalence of left ventricular hypertrophy by electrocardiogram was commoner in men than in women, and it rose with age. In 12 years 3.0% developed a definite and 4.5% developed a possible pattern. Incidence was strongly related to blood pressure, but less than half of those with the pattern had definite heart enlargement on X ray. Some 55% of the cases of congestive heart failure and 27% of the coronary heart disease cases were either preceded or followed by the pattern.

Prognosis was very grave. A definite pattern even when unassociated with coronary heart disease, congestive heart failure, or rheumatic heart disease resulted in mortality of 59% within 12 years. One in 2 men over 45 years old died within 8 years of developing a definite pattern. Altogether, 44% of the 264 cardiovascular deaths were preceded by a definite or possible finding of left ventricular hypertrophy by electrocardiogram.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Journal Club
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.