0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Ideas and Opinions |

Recent Developments in Antithrombotic Therapy

I. S. WRIGHT, M.D.
Ann Intern Med. 1969;71(4):823-831. doi:10.7326/0003-4819-71-4-823
Text Size: A A A
SUMMARY:

Thrombosis is one of the most important disease phenomena responsible for disability and death. Recent studies involving the prevention and treatment of this condition are reviewed. It is now well documented that the response to anticoagulant therapy is largely dependent on the selection of suitable patients and on the use of adequate therapeutic dosage of the anticoagulant drugs under investigation. Studies that have not fulfilled this requirement have consistently failed to achieve favorable therapeutic response. The potential clinical use of Malayan pit viper venom-fraction 6 (Arvin®), urokinase, and purified streptokinase, each a potent antithrombotic agent, is now under intensive investigation. The status of these studies is reviewed. Platelet thrombi have been resistant to treatment, and new studies with acetylsalicylic acid and other drugs are under way. Many drugs interact in a variety of ways with oral anticoagulants, and this must be considered in the application of anticoagulant therapy.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Topic Collections
PubMed Articles
Thrombosis and Hemostatic Abnormalities in Hematological Malignancies. Clin Lymphoma Myeloma Leuk Published online Jun 11, 2014.;
Recent advances in the antiphospholipid antibody syndrome. Curr Opin Hematol Published online Jul 14, 2014.;

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)