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Idiopathic Proteinuria

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Department of Medicine
Duke University Medical Center
Durham, N. C.

Ann Intern Med. 1969;71(5):1019-1022. doi:10.7326/0003-4819-71-5-1019
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The detection of proteinuria on the routine examination of apparently healthy individuals is often surrounded by diagnostic uncertainty. Its cause and clinical significance is particularly obscure when it occurs in the absence of the nephrotic syndrome or a systemic disease such as diabetes mellitus or hypertension, impaired renal function, an abnormal urine sediment, anatomic alteration on excretory urography, or a past history of renal disease. On the one hand, it is well known that transient proteinuria can and does occur in the absence of underlying renal disease—most evidently in association with such benign events as exercise, the maintenance of exaggerated




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