0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Articles |

Hyperinfection Syndrome with Strongyloides stercoralis

EZEQUIEL RIVERA, M.D.; NORMAN MALDONADO, M.D.; ENRIQUE VÉLEZ-GARCÍA, M.D.; ANTONIO J. GRILLO, M.D.; and GÉRMAN MALARET, M.D., F.A.C.P.
[+] Article and Author Information

Supported in part by hematology training grant T1 AM 5302, National Institutes of Health, Bethesda, Md.

Presented in part in September 1968, at the XIIth Congress of the International Society of Hematology, New York, N.Y.

▸Requests for reprints should be addressed to N. Maldonado, M.D., Hematology Section, University Hospital, Caparra Heights, Station, Caparra Heights, Puerto Rico 00935


San Juan,Puerto Rico


Ann Intern Med. 1970;72(2):199-204. doi:10.7326/0003-4819-72-2-199
Text Size: A A A

Infection with the parasitic nematode, Strongyloides stercoralis, can lead to death in patients with various clinical disorders. Alteration of the parasite—host relationship may lead to hyperinfection characterized by profound malabsorption, diarrhea, electrolyte imbalance, gram-negative or opportunistic fungal sepsis, coma, and death. During the last 3 years nine such patients were studied in the hematology section of a 300-bed university hospital. Eight patients died, four in spite of energetic treatment with thiabendazole. Since diagnosis of hyperinfection is often made only at autopsy, its presence should be suspected in hematologic patients and patients with diseases of altered immunity, such as leprosy and systemic lupus erythematosus. Since early diagnosis is essential to avoid fatalities, laboratory technicians and physicians dealing with such patients as well as with large population groups that harbor this parasite (for example, Puerto Ricans) should be alerted.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Topic Collections
PubMed Articles

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)