The full content of Annals is available to subscribers

Subscribe/Learn More  >
Articles |

Effects of Changes in Dietary Lipids on Intestinal Fluid Loss in the Short-Bowel Syndrome

[+] Article, Author, and Disclosure Information

This work was carried out in the Clinical Research Unit of Albany Medical College and supported by Public Health Service Research Center grant 5 MO1 FR00094 CLR from the Division of Research Facilities and Resources; and supported in part by Training Grant TO-1 AM05597, the National Institutes of Health, Bethesda, Md.

Appeared in part in Clinical Research 16:528, 1968.

▸Requests for reprints should be addressed to John A. Balint, M.D., Department of Medicine, Albany Medical College, Albany, N. Y. 12208

Albany, New York

Ann Intern Med. 1970;72(2):205-213. doi:10.7326/0003-4819-72-2-205
Text Size: A A A

Seven patients underwent massive intestinal resection. Fecal losses of water and electrolytes were life threatening in four patients, who required constant or repeated intravenous replacement. All patients received symptomatic treatment and vitamin replacement. Lowering the amount of dietary fat, bile salt replacement, and supplementation of diet with micellar fat were ineffective. A regimen consisting of 50 to 75% replacement of dietary long-chain fat with medium-chain triglyceride proved beneficial, leading to gradual decline in fecal loss of water and electrolytes and great improvement in nutritional status. Gastric secretory studies showed minimal increase in basal and 12-hr overnight acid output in two patients and no increase in maximal acid output. Pyloroplasty and vagotomy attempted in one patient and directed toward reduction of gastric secretion proved disastrous. Such treatment should be reserved for patients demonstrating massive gastric hypersecretion unresponsive to medical management, and a conservative program should be followed.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Journal Club
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.