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Why Not Vaccinate Against Tuberculosis

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▸ Requests for reprints should be addressed to Donald W. Smith, Department of Medical Microbiology, University of Wisconsin, Madison, Wis. 53706

Madison, Wisconsin

Ann Intern Med. 1970;72(3):419-422. doi:10.7326/0003-4819-72-3-419
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Whether to use Bacillus Calmette-Guérin (BCG) vaccination as a means of tuberculosis control in high-risk populations in the United States is controversial. The most frequently cited arguments for not using BCG in these groups include: the problem is not of sufficient magnitude; the vaccine is not effective; the vaccine is not safe; and the attendant tuberculin conversion destroys the effectiveness of the tuberculin test as a case-finding tool. The validity of these arguments is challenged, and it is concluded that BCG vaccination should be recommended for high-risk groups in the United States.







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