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Sarcoidosis of the Skull

[+] Article and Author Information

Supported in part by Clinical Research Center grant 5M01-FR-40, Division of Research Facilities and Resources, National Institutes of Health, Bethesda, Md.

▸Requests for reprints should be addressed to Lee W. Henderson, M.D., Hospital of the University of Pennsylvania, 3600 Spruce St., 621 Maloney Bldg., Philadelphia, Pa. 19104

Philadelphia, Pennsylvania

Ann Intern Med. 1970;72(6):929-931. doi:10.7326/0003-4819-72-6-929
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One of the rarest manifestations of sarcoidosis is involvement of the skull; only five cases have been reported (1-5). Bone lesions of any type are rare, and osseous localization is usually more frequent in the chronic stage, especially when there is simultaneous cutaneous involvement (6, 7). A young man with apparent hyperparathyroidism or hypervitaminosis D proved to have sarcoidosis with noncaseating granulomas in a liver and kidney biopsy. Roentgenograms of the skull showed multiple osteolytic lesions, biopsy of which showed scattered noncaseating granulomas consistent with sarcoidosis.


sarcoidosis ; cranium





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