The full content of Annals is available to subscribers

Subscribe/Learn More  >
Diagnosis and Treatment |

Current Procedures for Scanning of the Spleen

[+] Article, Author, and Disclosure Information

▸Requests for reprints should be addressed to Patricia A. McIntyre, M.D., Johns Hopkins Medical Institutions, 615 N. Wolfe St., Baltimore, Md. 21205

Baltimore, Maryland

Ann Intern Med. 1970;73(6):995-1001. doi:10.7326/0003-4819-73-6-995
Text Size: A A A

Spleen scanning is a valuable procedure for estimating the size, configuration, and location of splenic tissue and for detecting space-occupying lesions within the spleen. Two functions of the spleen provide the basis for spleen scanning: appropriately damaged erythrocytes are preferentially sequestered in splenic sinusoids; and the reticuloendothelial cells of the spleen, as well as those of other organs, accumulate intravenously injected colloidal particles by phagocytosis. Damaged erythrocytes or colloidal particles labeled with suitable gamma-emitting radionuclides can be used to obtain scanning images of the spleen. Although several methods are adequate for the majority of clinical problems, the colloidal preparations labeled with short-lived nuclides are preferred for routine use. Erythrocytes damaged by 1-mercuri-2-hydroxypropane provide the most precise estimate of splenic size, and the use of 51Cr-labeled erythrocytes damaged by heat is the best method for detection of accessory spleens.







Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.