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The Tularemia Skin Test: 325 Skin Tests in 210 Persons: Serologic Correlation and Review of the Literature

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▸Requests for reprints should be addressed to Thomas M. Buchanan, M.D., Special Pathogens Section, Bacterial Diseases Branch, Epidemiology Program, Center for Disease Control, Atlanta, Ga. 30333

Atlanta, Georgia

Ann Intern Med. 1971;74(3):336-343. doi:10.7326/0003-4819-74-3-336
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The tularemia skin test is a valuable diagnostic tool for the clinician and the epidemiologist. It is sensitive and specific for tularemia; it becomes positive earlier in the course of illness and is positive longer after infection than the agglutination test. Half of all patients with clinical tularemia are skin-test positive the day they present to the physician. It is a delayed hypersensitivity reaction read after 48 hr and can easily be administered and read at the bedside. It rarely causes a rise in the antibody titer and, once positive, may remain positive for as long as 40 years.





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