0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Editorials |

Australia Antigen: A Genetic Basis for Chronic Liver Disease and Hepatoma?

ALTON I. STUTNICK, M.D., F.A.C.P.; W. THOMAS LONDON JR., M.D., F.A.C.P.; and BARUCH S. BLUMBERG, M.D., PH.D.
[+] Article and Author Information

The Institute for Cancer Research, Fox Chase, Philadelphia, Pa.


Ann Intern Med. 1971;74(3):442-444. doi:10.7326/0003-4819-74-3-442
Text Size: A A A
This excerpt has been provided in the absence of an abstract.

The association of Australia antigen (Au(1)) with chronic hepatitis was first noted in 1966 in a study of patients with Down's syndrome (1). Many of these patients have persistent Australia antigen (as do many members of tropical populations studied previously (2) ). This observation stimulated an investigation of immunologic mechanisms in Down's syndrome patients with and without Au(1). One patient who did not have Australia antigen on previous testing developed it while under our observation. This provided the first evidence that Au(1) could be acquired. The patient went on to develop asymptomatic anicteric hepatitis detected only by biochemical and liver

...

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Related Point of Care
Topic Collections
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)