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Hepatic Coma Secondary to Metastatic Liver Disease

[+] Article and Author Information

▸Requests for reprints should be addressed to Paul Sherlock, M.D., Memorial Hospital, 444 East 68th St., New York, N.Y. 10021

New York, New York

Ann Intern Med. 1971;74(4):581-583. doi:10.7326/0003-4819-74-4-581
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In 21 patients the frequency of hepatic coma secondary to metastatic liver disease was 7.5% in breast carcinoma, 6.6% in gastric carcinoma, and 6.4% in colon carcinoma. Hepatic coma was not recognized clinically in 11 of 21 patients. Five of these patients were treated with hepatic radiation and five patients with 5-fluorouracil. Hepatic coma secondary to metastatic liver disease may be more frequent than previously recognized.





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