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Resolution of Chronic Eosinophilic Pneumonia with Corticoid Therapy: Demonstration by Needle Biopsy

JEAN L. PERRAULT, M.D.; MICHEL JANIS, M.D.; and HARVEY WOLINSKY, M.D., Ph.D.
[+] Article and Author Information

Supported in part by grant HE 12766, U.S. Public Health Service, Washington, D.C.; and contract U-2041, New York City Health Research Council, New York, N.Y.

▸Requests for reprints should be addressed to Harvey Wolinsky, M.D., Albert Einstein College of Medicine, Department of Medicine, 1300 Morris Park Ave., Bronx, N.Y. 10461


Bronx, New York


Ann Intern Med. 1971;74(6):951-954. doi:10.7326/0003-4819-74-6-951
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A case of needle biopsy-documented resolution of chronic eosinophilic pneumonia after corticoid therapy is described. The patient presented with nonspecific clinical symptoms, but persistent peripheral blood eosinophilia, migratory pulmonary infiltrates, and pulmonary function impairment suggested the diagnosis; histological proof was secured by means of percutaneous needle biopsy. The patient was then given corticosteroids. Several clinical, radiological, and functional remissions and exacerbations closely followed variations in steroid dosage. A second needle biopsy, done during a period of remission, confirmed the previous assumption by others that steroid therapy leads to resolution rather than organization of the alveolar and interstitial processes of chronic eosinophilic pneumonia.

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