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Bone Abnormalities After Gastric Surgery: A Prospective Histological Study

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Supported in part by the N.S.W. State Cancer Council and the Sydney University Cancer Research Fund, Sydney, New South Wales, Australia.

▸ Requests for reprints should be addressed to Solomon Posen, M.D., Sydney Hospital, Sydney, New South Wales, 2001, Australia.

Sydney, New South Wales, Australia

Ann Intern Med. 1971;75(2):221-225. doi:10.7326/0003-4819-75-2-221
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Thirty-six patients who had undergone gastric surgery 3 to 9 years before this study were subjected to an iliac crest biopsy. Quantitative analysis of undecalcified sections showed abnormal findings in 16 patients. Fifteen had an abnormally large amount of osteoid, six had a reduction in total bone, and five had a combination of the two abnormalities. Mild osteomalacia after gastrectomy appears to be more prevalent than previously suspected. Significant histological changes may occur in the absence of clinical, radiological, or biochemical abnormalities.





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